Collagenase SANTYL Ointment resources

SANTYL Ointment dosing calculator

Estimate the appropriate amount of SANTYL Ointment needed to help achieve wound debridement. Please note that the estimates are only intended as a guide, contain rounded values where appropriate, and assume a constant wound size throughout the treatment period. Therefore, you should adjust these estimates based upon your own clinical experience and individual wound characteristics.

3 versions of the dosing calculator are available

Go to the online version of the calculator now


Download a desktop app for your Mac/PC

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Clinical study overviews

Clinical outcomes associated with serial sharp debridement of diabetic foot ulcers with and without clostridial collagenase ointment


A comparison of collagenase to autolytic debridement using a hydrogel dressing


Enzymatic debridement guide

A guide that outlines appropriate wound types and proper application process for SANTYL Ointment


SANTYL Ointment measurement and planning guide

Guide that helps estimate the total grams of SANTYL Ointment needed for a desired course of therapy and the length of ointment needed per application based on wound area


Patient education

For a helpful guide for the appropriate application of SANTYL Ointment, click on a link below.

A patient’s guide to Collagenase SANTYL Ointment (English)

A patient’s guide to Collagenase SANTYL Ointment (Spanish)


Collagenase SANTYL Ointment is indicated for debriding chronic dermal ulcers and severely burned areas.

Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Use of Collagenase SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.

For more details, please see complete prescribing information.